• Navigation überspringen
  • Zur Navigation
  • Zum Seitenende
Organisationsmenü öffnen Organisationsmenü schließen
Division for Pharmaceutical Biology
  • FAUZur zentralen FAU Website
  1. Friedrich-Alexander-Universität
  2. Naturwissenschaftliche Fakultät
  3. Department Biologie
  • Campo
  • UnivIS
  • Stellenangebote
  • Lageplan
  • Hilfe im Notfall
  1. Friedrich-Alexander-Universität
  2. Naturwissenschaftliche Fakultät
  3. Department Biologie

Division for Pharmaceutical Biology

Menu Menu schließen
  • Research
    • Biogenic avenues
    • Extracellular vesicles
    • Cardenolides in cancer therapy
    • Plant cell and tissue culture
    • Publications
      • Jennifer Munkert
    Portal Research
  • Teaching
    • Congresses
    • Excursions
    • Links
    Portal Teaching
  • Staff
    • Job offers
    Portal Staff
  • Location
    • Travel directions
    Portal Location
  1. Startseite
  2. Research
  3. Publications

Publications

Bereichsnavigation: Research
  • Sustainability
  • Biogenic avenues
  • Extracellular vesicles
  • Cardenolides in cancer therapy
  • Plant cell and tissue culture
  • Publications
    • Jennifer Munkert

Publications

Prof. Dr. Gregor Fuhrmann

2023

  • Zivko C., Witt F., Koeberle A., Fuhrmann G., Luciani P.:
    Formulating elafibranor and obeticholic acid with phospholipids decreases drug-induced association of SPARC to extracellular vesicles from LX-2 human hepatic stellate cells
    In: European Journal of Pharmaceutics and Biopharmaceutics 182 (2023), S. 32-40
    ISSN: 0939-6411
    DOI: 10.1016/j.ejpb.2022.11.025

2022

  • Drost M., Diamanti E., Fuhrmann K., Goes A., Shams A., Haupenthal J., Koch M., Hirsch AK., Fuhrmann G.:
    Bacteriomimetic liposomes improve antibiotic activity of a novel energy-coupling factor transporter inhibitor
    In: Pharmaceutics 14 (2022), Art.Nr.: 4
    ISSN: 1999-4923
    DOI: 10.3390/pharmaceutics14010004
  • Fuhrmann G., Lehr CM., Schiffelers R.:
    Themed issue: Extracellular vesicles in drug delivery and bioengineering
    In: Advanced Drug Delivery Reviews 181 (2022), Art.Nr.: 114073
    ISSN: 0169-409X
    DOI: 10.1016/j.addr.2021.114073
  • Lapuhs P., Heinrich E., Garcia R., Goes A., Frank N., Bollenbach L., Stibane V., Kuhn T., Koch M., Kiemer AK., Müller R., Fuhrmann K., Fuhrmann G.:
    The inherent antibiotic activity of myxobacteria-derived autofluorescent outer membrane vesicles is switched on and off by light stimulation
    In: Nanoscale (2022)
    ISSN: 2040-3364
    DOI: 10.1039/d2nr02743g
  • Mehanny M., Boese A., Bornamehr B., Hoppstädter J., Presser V., Kiemer AK., Lehr CM., Fuhrmann G.:
    Spray-dried pneumococcal membrane vesicles are promising candidates for pulmonary immunization
    In: International Journal of Pharmaceutics 621 (2022), Art.Nr.: 121794
    ISSN: 0378-5173
    DOI: 10.1016/j.ijpharm.2022.121794
  • Nguyen J., Fuhrmann G.:
    Extracellular Vesicles — A Versatile Biomaterial
    In: Advanced Healthcare Materials 11 (2022), Art.Nr.: 2200192
    ISSN: 2192-2640
    DOI: 10.1002/adhm.202200192
  • Zivko C., Fuhrmann K., Fuhrmann G., Luciani P.:
    Tracking matricellular protein SPARC in extracellular vesicles as a non-destructive method to evaluate lipid-based antifibrotic treatments
    In: Communications Biology 5 (2022), Art.Nr.: 1155
    ISSN: 2399-3642
    DOI: 10.1038/s42003-022-04123-z

2021

  • Fuhrmann G., Loretz B., Schneider-Daum N., Lehr CM.:
    Biobarriers 2018
    In: European Journal of Pharmaceutics and Biopharmaceutics 158 (2021), S. 52-
    ISSN: 0939-6411
    DOI: 10.1016/j.ejpb.2020.10.014
  • Herrmann IK., Wood MJA., Fuhrmann G.:
    Extracellular vesicles as a next-generation drug delivery platform
    In: Nature nanotechnology (2021)
    ISSN: 1748-3395
    DOI: 10.1038/s41565-021-00931-2
  • Jahromi LP., Fuhrmann G.:
    Bacterial extracellular vesicles: Understanding biology promotes applications as nanopharmaceuticals
    In: Advanced Drug Delivery Reviews 173 (2021), S. 125-140
    ISSN: 0169-409X
    DOI: 10.1016/j.addr.2021.03.012
  • Mehanny M., Kroniger T., Koch M., Hoppstädter J., Becher D., Kiemer AK., Lehr CM., Fuhrmann G.:
    Yields and Immunomodulatory Effects of Pneumococcal Membrane Vesicles Differ with the Bacterial Growth Phase
    In: Advanced Healthcare Materials (2021)
    ISSN: 2192-2640
    DOI: 10.1002/adhm.202101151
  • Mehanny M., Lehr CM., Fuhrmann G.:
    Extracellular vesicles as antigen carriers for novel vaccination avenues
    In: Advanced Drug Delivery Reviews 173 (2021), S. 164-180
    ISSN: 0169-409X
    DOI: 10.1016/j.addr.2021.03.016
  • Mueller L., Kuhn T., Koch M., Fuhrmann G.:
    Stimulation of Probiotic Bacteria Induces Release of Membrane Vesicles with Augmented Anti-inflammatory Activity
    In: ACS Applied Bio Materials (2021)
    ISSN: 2576-6422
    DOI: 10.1021/acsabm.0c01136
  • Richter M., Vader P., Fuhrmann G.:
    Approaches to surface engineering of extracellular vesicles
    In: Advanced Drug Delivery Reviews 173 (2021), S. 416-426
    ISSN: 0169-409X
    DOI: 10.1016/j.addr.2021.03.020
  • Trousil J., Aryal S., Fuhrmann G.:
    Biogenic and biomimetic nanocarrier-based interventions: Focus on intracellular infections
    In: Nanomedicine 16 (2021), S. 685-688
    ISSN: 1743-5889
    DOI: 10.2217/nnm-2021-0052
  • Zivko C., Fuhrmann G., Luciani P.:
    Liver-derived extracellular vesicles: A cell by cell overview to isolation and characterization practices
    In: Biochimica Et Biophysica Acta-General Subjects 1865 (2021), Art.Nr.: 129559
    ISSN: 0304-4165
    DOI: 10.1016/j.bbagen.2020.129559

2020

  • Fuhrmann G.:
    Diffusion and transport of extracellular vesicles
    In: Nature nanotechnology 15 (2020), S. 168-169
    ISSN: 1748-3395
    DOI: 10.1038/s41565-020-0651-3
  • Goes A., Lapuhs P., Kuhn T., Schulz E., Richter R., Panter F., Dahlem C., Koch M., Garcia R., Kiemer AK., Mueller R., Fuhrmann G.:
    Myxobacteria-Derived Outer Membrane Vesicles: Potential Applicability Against Intracellular Infections
    In: Cells 9 (2020)
    ISSN: 2073-4409
    DOI: 10.3390/cells9010194
  • Kuhn T., Koch M., Fuhrmann G.:
    Probiomimetics—Novel Lactobacillus-Mimicking Microparticles Show Anti-Inflammatory and Barrier-Protecting Effects in Gastrointestinal Models
    In: Small 16 (2020), Art.Nr.: 2003158
    ISSN: 1613-6829
    DOI: 10.1002/smll.202003158
  • Mehanny M., Koch M., Lehr CM., Fuhrmann G.:
    Streptococcal Extracellular Membrane Vesicles Are Rapidly Internalized by Immune Cells and Alter Their Cytokine Release
    In: Frontiers in Immunology 11 (2020), Art.Nr.: 80
    ISSN: 1664-3224
    DOI: 10.3389/fimmu.2020.00080
  • Montefusco-Pereira C., Formicola B., Goes A., Re F., Marrano CA., Mantegazza F., Carvalho-Wodarz C., Fuhrmann G., Caneva E., Nicotra F., Lehr CM., Russo L.:
    Coupling quaternary ammonium surfactants to the surface of liposomes improves both antibacterial efficacy and host cell biocompatibility
    In: European Journal of Pharmaceutics and Biopharmaceutics 149 (2020), S. 12-20
    ISSN: 0939-6411
    DOI: 10.1016/j.ejpb.2020.01.013
  • Schulz E., Karagianni A., Koch M., Fuhrmann G.:
    Hot EVs – How temperature affects extracellular vesicles
    In: European Journal of Pharmaceutics and Biopharmaceutics 146 (2020), S. 55-63
    ISSN: 0939-6411
    DOI: 10.1016/j.ejpb.2019.11.010
  • Whitworth DE., Jurkevitch E., Perez J., Fuhrmann G., Koval SF.:
    Editorial: Mechanisms of Prokaryotic Predation
    In: Frontiers in Microbiology 11 (2020), Art.Nr.: 2071
    ISSN: 1664-302X
    DOI: 10.3389/fmicb.2020.02071

2019

  • Hoppstaedter J., Dembek A., Linnenberger R., Dahlem C., Barghash A., Fecher-Trost C., Fuhrmann G., Koch M., Kraegeloh A., Huwer H., Kiemer AK.:
    Toll-Like Receptor 2 Release by Macrophages: An Anti-inflammatory Program Induced by Glucocorticoids and Lipopolysaccharide
    In: Frontiers in Immunology 10 (2019), S. 1634-
    ISSN: 1664-3224
    DOI: 10.3389/fimmu.2019.01634
  • Lapuhs P., Fuhrmann G.:
    Engineering strategies for oral therapeutic enzymes to enhance their stability and activity
    In: Advances in Experimental Medicine and Biology, Springer New York LLC, 2019, S. 151-172 (Advances in Experimental Medicine and Biology, Bd.1148)
    DOI: 10.1007/978-981-13-7709-9_8
  • Richter M., Fuhrmann K., Fuhrmann G.:
    Evaluation of the storage stability of extracellular vesicles
    In: Journal of Visualized Experiments 2019 (2019), Art.Nr.: e59584
    ISSN: 1940-087X
    DOI: 10.3791/59584
  • Schulz E., Goes A., Garcia R., Panter F., Koch M., Mueller R., Fuhrmann K., Fuhrmann G.:
    Corrigendum to biocompatible bacteria-derived vesicles show inherent antimicrobial activity (Journal of Controlled Release (2018) 290 (46–55), (S0168365918305698) (10.1016/j.jconrel.2018.09.030))
    In: Journal of Controlled Release 293 (2019), S. 155-157
    ISSN: 0168-3659
    DOI: 10.1016/j.jconrel.2018.11.027
  • Woith E., Fuhrmann G., Melzig MF.:
    Extracellular vesicles—connecting kingdoms
    In: International Journal of Molecular Sciences 20 (2019), Art.Nr.: 5695
    ISSN: 1422-0067
    DOI: 10.3390/ijms20225695

2018

  • Frank J., Richter M., De Rossi C., Lehr CM., Fuhrmann K., Fuhrmann G.:
    Extracellular vesicles protect glucuronidase model enzymes during freeze-drying
    In: Scientific Reports 8 (2018), Art.Nr.: 12377
    ISSN: 2045-2322
    DOI: 10.1038/s41598-018-30786-y
  • Fuhrmann G.:
    Luminal coating of the intestine
    In: Nature Materials 17 (2018), S. 754-755
    ISSN: 1476-4660
    DOI: 10.1038/s41563-018-0143-0
  • Fuhrmann G., Chandrawati R., Parmar PA., Keane TJ., Maynard SA., Bertazzo S., Stevens MM.:
    Engineering Extracellular Vesicles with the Tools of Enzyme Prodrug Therapy
    In: Advanced Materials 30 (2018), Art.Nr.: 1706616
    ISSN: 0935-9648
    DOI: 10.1002/adma.201706616
  • Goes A., Fuhrmann G.:
    Biogenic and Biomimetic Carriers as Versatile Transporters to Treat Infections
    In: ACS Infectious Diseases 4 (2018), S. 881-892
    ISSN: 2373-8227
    DOI: 10.1021/acsinfecdis.8b00030
  • Schulz E., Goes A., Garcia R., Panter F., Koch M., Mueller R., Fuhrmann K., Fuhrmann G.:
    Biocompatible bacteria-derived vesicles show inherent antimicrobial activity
    In: Journal of Controlled Release 290 (2018), S. 46-55
    ISSN: 0168-3659
    DOI: 10.1016/j.jconrel.2018.09.030

2017

  • Fuhrmann G., Neuer AL., Herrmann IK.:
    Extracellular vesicles – A promising avenue for the detection and treatment of infectious diseases?
    In: European Journal of Pharmaceutics and Biopharmaceutics 118 (2017), S. 56-61
    ISSN: 0939-6411
    DOI: 10.1016/j.ejpb.2017.04.005
  • Fuhrmann K., Fuhrmann G.:
    Recent advances in oral delivery of macromolecular drugs and benefits of polymer conjugation
    In: Current Opinion in Colloid & Interface Science 31 (2017), S. 67-74
    ISSN: 1359-0294
    DOI: 10.1016/j.cocis.2017.07.002

2015

  • Fuhrmann G., Herrmann IK., Stevens MM.:
    Cell-derived vesicles for drug therapy and diagnostics: Opportunities and challenges
    In: Nano Today 10 (2015), S. 397-409
    ISSN: 1748-0132
    DOI: 10.1016/j.nantod.2015.04.004
  • Fuhrmann G., Serio A., Mazo M., Nair R., Stevens MM.:
    Active loading into extracellular vesicles significantly improves the cellular uptake and photodynamic effect of porphyrins
    In: Journal of Controlled Release 205 (2015), S. 35-44
    ISSN: 0168-3659
    DOI: 10.1016/j.jconrel.2014.11.029
  • Santos L., Fuhrmann G., Juenet M., Amdursky N., Horejs CM., Campagnolo P., Stevens MM.:
    Extracellular Stiffness Modulates the Expression of Functional Proteins and Growth Factors in Endothelial Cells
    In: Advanced Healthcare Materials 4 (2015), S. 2056-2063
    ISSN: 2192-2640
    DOI: 10.1002/adhm.201500338

2014

  • Fuhrmann G., Leroux JC.:
    Improving the stability and activity of oral therapeutic enzymes - Recent advances and perspectives
    In: Pharmaceutical Research 31 (2014), S. 1099-1105
    ISSN: 0724-8741
    DOI: 10.1007/s11095-013-1233-y

2013

  • Fuhrmann G., Gauthier MA., Leroux JC.:
    Polymer-enzyme conjugates for oral drug delivery applications
    In: Chimia 67 (2013), S. 685-
    ISSN: 0009-4293
    DOI: 10.2533/chimia.2013.685
  • Fuhrmann G., Grotzky A., Lukic R., Matoori S., Luciani P., Yu H., Zhang B., Walde P., Schlueter AD., Gauthier MA., Leroux JC.:
    Sustained gastrointestinal activity of dendronized polymer-enzyme conjugates
    In: Nature Chemistry 5 (2013), S. 582-589
    ISSN: 1755-4330
    DOI: 10.1038/nchem.1675
  • Matoori S., Fuhrmann G., Leroux JC.:
    Celiac disease: A challenging disease for pharmaceutical scientists
    In: Pharmaceutical Research 30 (2013), S. 619-626
    ISSN: 0724-8741
    DOI: 10.1007/s11095-012-0951-x

2012

  • Pinier M., Fuhrmann G., Galipeau HJ., Rivard N., Murray JA., David CS., Drasarova H., Tuckova L., Leroux JC., Verdu EF.:
    The copolymer P(HEMA-co-SS) binds gluten and reduces immune response in gluten-sensitized mice and human tissues
    In: Gastroenterology 142 (2012), S. 316-325.e12
    ISSN: 0016-5085
    DOI: 10.1053/j.gastro.2011.10.038

2011

  • Fuhrmann G., Leroux JC.:
    In vivo fluorescence imaging of exogenous enzyme activity in the gastrointestinal tract
    In: Proceedings of the National Academy of Sciences of the United States of America 108 (2011), S. 9032-9037
    ISSN: 0027-8424
    DOI: 10.1073/pnas.1100285108

2010

  • Bastiat G., Plourde F., Motulsky A., Furtos A., Dumont Y., Quirion R., Fuhrmann G., Leroux JC.:
    Tyrosine-based rivastigmine-loaded organogels in the treatment of Alzheimer's disease
    In: Biomaterials 31 (2010), S. 6031-6038
    ISSN: 0142-9612
    DOI: 10.1016/j.biomaterials.2010.04.009
  • Fuhrmann G., Leroux JC.:
    In vitro evaluation of the stability of proline-specific endopeptidases under simulated gastrointestinal conditions.
    In: Journal of Controlled Release 148 (2010), S. e37-39
    ISSN: 0168-3659
    DOI: 10.1016/j.jconrel.2010.07.046
  • Pinier M., Fuhrmann G., Verdu E., Leroux JC.:
    Prevention measures and exploratory pharmacological treatments of celiac disease
    In: American Journal of Gastroenterology 105 (2010), S. 2551-2561
    ISSN: 0002-9270
    DOI: 10.1038/ajg.2010.372

 

Friedrich-Alexander-Universität
Erlangen-Nürnberg

Schlossplatz 4
91054 Erlangen
  • Impressum
  • Datenschutz
  • Barrierefreiheit
Nach oben