Publications
2023
- Fuhrmann G.:
Drug delivery as a sustainable avenue to future therapies
In: Journal of Controlled Release 354 (2023), S. 746-754
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2023.01.045 - Heinrich E., Hartwig O., Walt C., Kardani A., Koch M., Jahromi LP., Hoppstaedter J., Kiemer AK., Loretz B., Lehr CM., Fuhrmann G.:
Cell-Derived Vesicles for Antibiotic Delivery-Understanding the Challenges of a Biogenic Carrier System
In: Small (2023)
ISSN: 1613-6829
DOI: 10.1002/smll.202207479 - Pourtalebi Jahromi L., Rothammer M., Fuhrmann G.:
Polysaccharide hydrogel platforms as suitable carriers of liposomes and extracellular vesicles for dermal applications
In: Advanced Drug Delivery Reviews 200 (2023), Art.Nr.: 115028
ISSN: 0169-409X
DOI: 10.1016/j.addr.2023.115028 - Zivko C., Witt F., Koeberle A., Fuhrmann G., Luciani P.:
Formulating elafibranor and obeticholic acid with phospholipids decreases drug-induced association of SPARC to extracellular vesicles from LX-2 human hepatic stellate cells
In: European Journal of Pharmaceutics and Biopharmaceutics 182 (2023), S. 32-40
ISSN: 0939-6411
DOI: 10.1016/j.ejpb.2022.11.025
2022
- Drost M., Diamanti E., Fuhrmann K., Goes A., Shams A., Haupenthal J., Koch M., Hirsch AK., Fuhrmann G.:
Bacteriomimetic liposomes improve antibiotic activity of a novel energy-coupling factor transporter inhibitor
In: Pharmaceutics 14 (2022), Art.Nr.: 4
ISSN: 1999-4923
DOI: 10.3390/pharmaceutics14010004 - Fuhrmann G., Lehr CM., Schiffelers R.:
Themed issue: Extracellular vesicles in drug delivery and bioengineering
In: Advanced Drug Delivery Reviews 181 (2022), Art.Nr.: 114073
ISSN: 0169-409X
DOI: 10.1016/j.addr.2021.114073 - Lapuhs P., Heinrich E., Garcia R., Goes A., Frank N., Bollenbach L., Stibane V., Kuhn T., Koch M., Kiemer AK., Müller R., Fuhrmann K., Fuhrmann G.:
The inherent antibiotic activity of myxobacteria-derived autofluorescent outer membrane vesicles is switched on and off by light stimulation
In: Nanoscale (2022)
ISSN: 2040-3364
DOI: 10.1039/d2nr02743g - Mehanny M., Boese A., Bornamehr B., Hoppstädter J., Presser V., Kiemer AK., Lehr CM., Fuhrmann G.:
Spray-dried pneumococcal membrane vesicles are promising candidates for pulmonary immunization
In: International Journal of Pharmaceutics 621 (2022), Art.Nr.: 121794
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2022.121794 - Nguyen J., Fuhrmann G.:
Extracellular Vesicles — A Versatile Biomaterial
In: Advanced Healthcare Materials 11 (2022), Art.Nr.: 2200192
ISSN: 2192-2640
DOI: 10.1002/adhm.202200192 - Zivko C., Fuhrmann K., Fuhrmann G., Luciani P.:
Tracking matricellular protein SPARC in extracellular vesicles as a non-destructive method to evaluate lipid-based antifibrotic treatments
In: Communications Biology 5 (2022), Art.Nr.: 1155
ISSN: 2399-3642
DOI: 10.1038/s42003-022-04123-z
2021
- Fuhrmann G., Loretz B., Schneider-Daum N., Lehr CM.:
Biobarriers 2018
In: European Journal of Pharmaceutics and Biopharmaceutics 158 (2021), S. 52-
ISSN: 0939-6411
DOI: 10.1016/j.ejpb.2020.10.014 - Herrmann IK., Wood MJA., Fuhrmann G.:
Extracellular vesicles as a next-generation drug delivery platform
In: Nature nanotechnology (2021)
ISSN: 1748-3395
DOI: 10.1038/s41565-021-00931-2 - Jahromi LP., Fuhrmann G.:
Bacterial extracellular vesicles: Understanding biology promotes applications as nanopharmaceuticals
In: Advanced Drug Delivery Reviews 173 (2021), S. 125-140
ISSN: 0169-409X
DOI: 10.1016/j.addr.2021.03.012 - Mehanny M., Kroniger T., Koch M., Hoppstädter J., Becher D., Kiemer AK., Lehr CM., Fuhrmann G.:
Yields and Immunomodulatory Effects of Pneumococcal Membrane Vesicles Differ with the Bacterial Growth Phase
In: Advanced Healthcare Materials (2021)
ISSN: 2192-2640
DOI: 10.1002/adhm.202101151 - Mehanny M., Lehr CM., Fuhrmann G.:
Extracellular vesicles as antigen carriers for novel vaccination avenues
In: Advanced Drug Delivery Reviews 173 (2021), S. 164-180
ISSN: 0169-409X
DOI: 10.1016/j.addr.2021.03.016 - Mueller L., Kuhn T., Koch M., Fuhrmann G.:
Stimulation of Probiotic Bacteria Induces Release of Membrane Vesicles with Augmented Anti-inflammatory Activity
In: ACS Applied Bio Materials (2021)
ISSN: 2576-6422
DOI: 10.1021/acsabm.0c01136 - Richter M., Vader P., Fuhrmann G.:
Approaches to surface engineering of extracellular vesicles
In: Advanced Drug Delivery Reviews 173 (2021), S. 416-426
ISSN: 0169-409X
DOI: 10.1016/j.addr.2021.03.020 - Trousil J., Aryal S., Fuhrmann G.:
Biogenic and biomimetic nanocarrier-based interventions: Focus on intracellular infections
In: Nanomedicine 16 (2021), S. 685-688
ISSN: 1743-5889
DOI: 10.2217/nnm-2021-0052 - Zivko C., Fuhrmann G., Luciani P.:
Liver-derived extracellular vesicles: A cell by cell overview to isolation and characterization practices
In: Biochimica Et Biophysica Acta-General Subjects 1865 (2021), Art.Nr.: 129559
ISSN: 0304-4165
DOI: 10.1016/j.bbagen.2020.129559
2020
- Fuhrmann G.:
Diffusion and transport of extracellular vesicles
In: Nature nanotechnology 15 (2020), S. 168-169
ISSN: 1748-3395
DOI: 10.1038/s41565-020-0651-3 - Goes A., Lapuhs P., Kuhn T., Schulz E., Richter R., Panter F., Dahlem C., Koch M., Garcia R., Kiemer AK., Mueller R., Fuhrmann G.:
Myxobacteria-Derived Outer Membrane Vesicles: Potential Applicability Against Intracellular Infections
In: Cells 9 (2020)
ISSN: 2073-4409
DOI: 10.3390/cells9010194 - Kuhn T., Koch M., Fuhrmann G.:
Probiomimetics—Novel Lactobacillus-Mimicking Microparticles Show Anti-Inflammatory and Barrier-Protecting Effects in Gastrointestinal Models
In: Small 16 (2020), Art.Nr.: 2003158
ISSN: 1613-6829
DOI: 10.1002/smll.202003158 - Mehanny M., Koch M., Lehr CM., Fuhrmann G.:
Streptococcal Extracellular Membrane Vesicles Are Rapidly Internalized by Immune Cells and Alter Their Cytokine Release
In: Frontiers in Immunology 11 (2020), Art.Nr.: 80
ISSN: 1664-3224
DOI: 10.3389/fimmu.2020.00080 - Montefusco-Pereira C., Formicola B., Goes A., Re F., Marrano CA., Mantegazza F., Carvalho-Wodarz C., Fuhrmann G., Caneva E., Nicotra F., Lehr CM., Russo L.:
Coupling quaternary ammonium surfactants to the surface of liposomes improves both antibacterial efficacy and host cell biocompatibility
In: European Journal of Pharmaceutics and Biopharmaceutics 149 (2020), S. 12-20
ISSN: 0939-6411
DOI: 10.1016/j.ejpb.2020.01.013 - Schulz E., Karagianni A., Koch M., Fuhrmann G.:
Hot EVs – How temperature affects extracellular vesicles
In: European Journal of Pharmaceutics and Biopharmaceutics 146 (2020), S. 55-63
ISSN: 0939-6411
DOI: 10.1016/j.ejpb.2019.11.010 - Whitworth DE., Jurkevitch E., Perez J., Fuhrmann G., Koval SF.:
Editorial: Mechanisms of Prokaryotic Predation
In: Frontiers in Microbiology 11 (2020), Art.Nr.: 2071
ISSN: 1664-302X
DOI: 10.3389/fmicb.2020.02071
2019
- Hoppstaedter J., Dembek A., Linnenberger R., Dahlem C., Barghash A., Fecher-Trost C., Fuhrmann G., Koch M., Kraegeloh A., Huwer H., Kiemer AK.:
Toll-Like Receptor 2 Release by Macrophages: An Anti-inflammatory Program Induced by Glucocorticoids and Lipopolysaccharide
In: Frontiers in Immunology 10 (2019), S. 1634-
ISSN: 1664-3224
DOI: 10.3389/fimmu.2019.01634 - Lapuhs P., Fuhrmann G.:
Engineering strategies for oral therapeutic enzymes to enhance their stability and activity
In: Advances in Experimental Medicine and Biology, Springer New York LLC, 2019, S. 151-172 (Advances in Experimental Medicine and Biology, Bd.1148)
DOI: 10.1007/978-981-13-7709-9_8 - Richter M., Fuhrmann K., Fuhrmann G.:
Evaluation of the storage stability of extracellular vesicles
In: Journal of Visualized Experiments 2019 (2019), Art.Nr.: e59584
ISSN: 1940-087X
DOI: 10.3791/59584 - Schulz E., Goes A., Garcia R., Panter F., Koch M., Mueller R., Fuhrmann K., Fuhrmann G.:
Corrigendum to biocompatible bacteria-derived vesicles show inherent antimicrobial activity (Journal of Controlled Release (2018) 290 (46–55), (S0168365918305698) (10.1016/j.jconrel.2018.09.030))
In: Journal of Controlled Release 293 (2019), S. 155-157
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2018.11.027 - Woith E., Fuhrmann G., Melzig MF.:
Extracellular vesicles—connecting kingdoms
In: International Journal of Molecular Sciences 20 (2019), Art.Nr.: 5695
ISSN: 1422-0067
DOI: 10.3390/ijms20225695
2018
- Frank J., Richter M., De Rossi C., Lehr CM., Fuhrmann K., Fuhrmann G.:
Extracellular vesicles protect glucuronidase model enzymes during freeze-drying
In: Scientific Reports 8 (2018), Art.Nr.: 12377
ISSN: 2045-2322
DOI: 10.1038/s41598-018-30786-y - Fuhrmann G.:
Luminal coating of the intestine
In: Nature Materials 17 (2018), S. 754-755
ISSN: 1476-4660
DOI: 10.1038/s41563-018-0143-0 - Fuhrmann G., Chandrawati R., Parmar PA., Keane TJ., Maynard SA., Bertazzo S., Stevens MM.:
Engineering Extracellular Vesicles with the Tools of Enzyme Prodrug Therapy
In: Advanced Materials 30 (2018), Art.Nr.: 1706616
ISSN: 0935-9648
DOI: 10.1002/adma.201706616 - Goes A., Fuhrmann G.:
Biogenic and Biomimetic Carriers as Versatile Transporters to Treat Infections
In: ACS Infectious Diseases 4 (2018), S. 881-892
ISSN: 2373-8227
DOI: 10.1021/acsinfecdis.8b00030 - Schulz E., Goes A., Garcia R., Panter F., Koch M., Mueller R., Fuhrmann K., Fuhrmann G.:
Biocompatible bacteria-derived vesicles show inherent antimicrobial activity
In: Journal of Controlled Release 290 (2018), S. 46-55
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2018.09.030
2017
2015
- Fuhrmann G., Herrmann IK., Stevens MM.:
Cell-derived vesicles for drug therapy and diagnostics: Opportunities and challenges
In: Nano Today 10 (2015), S. 397-409
ISSN: 1748-0132
DOI: 10.1016/j.nantod.2015.04.004 - Fuhrmann G., Serio A., Mazo M., Nair R., Stevens MM.:
Active loading into extracellular vesicles significantly improves the cellular uptake and photodynamic effect of porphyrins
In: Journal of Controlled Release 205 (2015), S. 35-44
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2014.11.029 - Santos L., Fuhrmann G., Juenet M., Amdursky N., Horejs CM., Campagnolo P., Stevens MM.:
Extracellular Stiffness Modulates the Expression of Functional Proteins and Growth Factors in Endothelial Cells
In: Advanced Healthcare Materials 4 (2015), S. 2056-2063
ISSN: 2192-2640
DOI: 10.1002/adhm.201500338
2014
2013
- Fuhrmann G., Gauthier MA., Leroux JC.:
Polymer-enzyme conjugates for oral drug delivery applications
In: Chimia 67 (2013), S. 685-
ISSN: 0009-4293
DOI: 10.2533/chimia.2013.685 - Fuhrmann G., Grotzky A., Lukic R., Matoori S., Luciani P., Yu H., Zhang B., Walde P., Schlueter AD., Gauthier MA., Leroux JC.:
Sustained gastrointestinal activity of dendronized polymer-enzyme conjugates
In: Nature Chemistry 5 (2013), S. 582-589
ISSN: 1755-4330
DOI: 10.1038/nchem.1675 - Matoori S., Fuhrmann G., Leroux JC.:
Celiac disease: A challenging disease for pharmaceutical scientists
In: Pharmaceutical Research 30 (2013), S. 619-626
ISSN: 0724-8741
DOI: 10.1007/s11095-012-0951-x
2012
- Pinier M., Fuhrmann G., Galipeau HJ., Rivard N., Murray JA., David CS., Drasarova H., Tuckova L., Leroux JC., Verdu EF.:
The copolymer P(HEMA-co-SS) binds gluten and reduces immune response in gluten-sensitized mice and human tissues
In: Gastroenterology 142 (2012), S. 316-325.e12
ISSN: 0016-5085
DOI: 10.1053/j.gastro.2011.10.038
2011
2010
- Bastiat G., Plourde F., Motulsky A., Furtos A., Dumont Y., Quirion R., Fuhrmann G., Leroux JC.:
Tyrosine-based rivastigmine-loaded organogels in the treatment of Alzheimer's disease
In: Biomaterials 31 (2010), S. 6031-6038
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2010.04.009 - Fuhrmann G., Leroux JC.:
In vitro evaluation of the stability of proline-specific endopeptidases under simulated gastrointestinal conditions.
In: Journal of Controlled Release 148 (2010), S. e37-39
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2010.07.046 - Pinier M., Fuhrmann G., Verdu E., Leroux JC.:
Prevention measures and exploratory pharmacological treatments of celiac disease
In: American Journal of Gastroenterology 105 (2010), S. 2551-2561
ISSN: 0002-9270
DOI: 10.1038/ajg.2010.372
